Mel285Homo sapiens (Human)Cancer cell line
Also known as: Mel 285, Mel-285, MEL285
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_C303 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Eye, uvea[UBERON:UBERON_0001768] |
Donor Information
| Age | 49 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Uveal melanoma |
|---|---|
| Lineage | Eye |
| Subtype | Uveal Melanoma |
| OncoTree Code | UM |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-002015_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,13
D13S317
11
D16S539
11,14
D18S51
16,17
D21S11
29
D3S1358
15,17
D5S818
13
D7S820
8,13
D8S1179
11,15
FGA
20,22
Penta D
5
Penta E
17
TH01
8,9.3
TPOX
11
vWA
19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016).
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Salvi S., Truini M., Poggi A., Pfeffer U.
Eur. J. Cancer 49:3353-3365(2013).
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
Mol. Cancer Ther. 11:888-897(2012).
Genetic and molecular characterization of uveal melanoma cell lines.
Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Pigment Cell Melanoma Res. 25:182-187(2012).