OS052Homo sapiens (Human)Cancer cell line

Also known as: PSS008

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_C8FR
SpeciesHomo sapiens (Human)
Tissue SourceBone, fibula[UBERON:UBERON_0001446]

Donor Information

Age17
Age CategoryPediatric
SexFemale

Disease Information

DiseaseOsteosarcoma
LineageBone
SubtypeOsteosarcoma
OncoTree CodeOS

DepMap Information

Source TypeAcademic lab
Source IDACH-002471_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleRB1p.Glu465Lysfs*13 (c.1392delA) (c.1391delA)Homozygous-Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11,12
D13S317
13
D16S539
11
D5S818
11
D7S820
9,11
TH01
9.3
TPOX
8
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Osteosarcoma PDX-derived cell line models for preclinical drug evaluation demonstrate metastasis inhibition by dinaciclib through a genome-targeted approach.

Sirota M., Sweet-Cordero E.A.

Clin. Cancer Res. 30:849-864(2024).