OS186Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_C8FT
SpeciesHomo sapiens (Human)
Tissue SourceBone, jaw, mandible[UBERON:UBERON_0001684]

Donor Information

Age13
Age CategoryPediatric
SexMale

Disease Information

DiseaseOsteosarcoma
LineageBone
SubtypeOsteosarcoma
OncoTree CodeOS

DepMap Information

Source TypeAcademic lab
Source IDACH-002470_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
11,12
D13S317
8
D16S539
10,13
D5S818
10,12
D7S820
10,11
TH01
7
TPOX
8,11
vWA
16,18,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Osteosarcoma PDX-derived cell line models for preclinical drug evaluation demonstrate metastasis inhibition by dinaciclib through a genome-targeted approach.

Sirota M., Sweet-Cordero E.A.

Clin. Cancer Res. 30:849-864(2024).