YU-1097Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_C8UL
SpeciesHomo sapiens (Human)

Disease Information

DiseaseLung adenocarcinoma

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationUnexplicitEGFREx19delUnspecified-PubMed=31882684
MutationSimpleEGFRp.Thr790Met (c.2369C>T)UnspecifiedAcquired during resistance selection processPubMed=31882684
MutationSimpleEGFRp.Cys797Ser (c.2389T>A)UnspecifiedResponsible for resistance to WZ4002. Located in the same allele as the p.Thr790Met mutationPubMed=31882684

Publications

Patient-derived cells to guide targeted therapy for advanced lung adenocarcinoma.

Kim H.R., Cho B.C.

Sci. Rep. 9:19909-19909(2019).