TENHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_E063 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Endometrium[UBERON:UBERON_0001295] |
Donor Information
| Age | 74 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Endometrial carcinoma |
|---|---|
| Lineage | Uterus |
| Subtype | Uterine Clear Cell Carcinoma |
| OncoTree Code | UCCC |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000397_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg342Ter (c.1024C>T) | Homozygous | - | PubMed=29970484 |
| MutationSimple | KRAS | p.Thr74Pro (c.220A>C) | Heterozygous | - | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
10,12
D16S539
11,12
D5S818
11,12
D7S820
10,12
TH01
7,8
TPOX
8
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Characterization of a newly established human tumor cell line (TEN) from a patient with clear cell carcinoma of the uterine body and its sensitivity to anti-cancer agents.
Izumi R.
Hum. Cell 10:199-208(1997).