ICC18Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_E4KL
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age CategoryUnknown
SexUnknown

Disease Information

DiseaseCholangiocarcinoma
LineageBiliary Tract
SubtypeIntrahepatic Cholangiocarcinoma
OncoTree CodeIHCH

DepMap Information

Source TypeAcademic lab
Source IDACH-001996_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Tyr205His (c.613T>C)Unspecified-PubMed=16203773
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Vazquez F., Getz G., Bardeesy N.M.

bioRxiv 2024:07.04.601970-07.04.601970(2024).

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.

Zhu A.X.-X., Corcoran R.B., Bardeesy N.M.

Cancer Discov. 9:1064-1079(2019).