ZR-75-1 VIII-24Homo sapiens (Human)Cancer cell line
Also known as: ZR-75-1 VIII24, ZR-75-1 [VIII-24]
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_E4LA |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Ascites[UBERON:UBERON_0007795] |
Disease Information
| Disease | Invasive breast carcinoma of no special type |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | PTEN | p.Leu108Arg (c.323T>G) | Homozygous | - | from parent cell line ZR-75-1 |
| MutationSimple | HRAS | p.Glu162Lys (c.484G>A) | Homozygous | - | from parent cell line ZR-75-1 |
Publications
Functional identification of genes causing estrogen independence of human breast cancer cells.
Dorssers L.C.J.
Breast Cancer Res. Treat. 114:23-30(2009).
Identification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cells.
Dorssers L.C.J., Veldscholte J.W.
Int. J. Cancer 72:700-705(1997).