ZR-75-1 XI-35Homo sapiens (Human)Cancer cell line
Also known as: ZR-75-1 [XI-35]
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_E4LZ |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Ascites[UBERON:UBERON_0007795] |
Disease Information
| Disease | Invasive breast carcinoma of no special type |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | PTEN | p.Leu108Arg (c.323T>G) | Homozygous | - | from parent cell line ZR-75-1 |
| MutationSimple | HRAS | p.Glu162Lys (c.484G>A) | Homozygous | - | from parent cell line ZR-75-1 |
Publications
Functional identification of genes causing estrogen independence of human breast cancer cells.
Dorssers L.C.J.
Breast Cancer Res. Treat. 114:23-30(2009).