ZR-75-1 AKT2 pool BHomo sapiens (Human)Cancer cell line

Also known as: ZR-AKT2 pool B

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_E4WS
SpeciesHomo sapiens (Human)
Tissue SourceAscites[UBERON:UBERON_0007795]

Disease Information

DiseaseInvasive breast carcinoma of no special type

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimplePTENp.Leu108Arg (c.323T>G)Homozygous-from parent cell line ZR-75-1
MutationSimpleHRASp.Glu162Lys (c.484G>A)Homozygous-from parent cell line ZR-75-1

Publications

Functional identification of genes causing estrogen independence of human breast cancer cells.

Dorssers L.C.J.

Breast Cancer Res. Treat. 114:23-30(2009).