ZR-75-1 BCAR3 clone B3-10Homo sapiens (Human)Cancer cell line

Also known as: ZR-75-1 BCAR3 [B3-10]

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_E4WU
SpeciesHomo sapiens (Human)
Tissue SourceAscites[UBERON:UBERON_0007795]

Disease Information

DiseaseInvasive breast carcinoma of no special type

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimplePTENp.Leu108Arg (c.323T>G)Homozygous-from parent cell line ZR-75-1
MutationSimpleHRASp.Glu162Lys (c.484G>A)Homozygous-from parent cell line ZR-75-1

Publications

Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells.

Vreede L., Dorssers L.C.J.

EMBO J. 17:2799-2808(1998).