JVE015Homo sapiens (Human)Cancer cell line
Also known as: JVE-015
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_EG16 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Colon, sigmoid[UBERON:UBERON_0001159] |
Donor Information
| Age | 66 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Colon carcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Colon Adenocarcinoma |
| OncoTree Code | COAD |
DepMap Information
| Source Type | DSMZ |
|---|---|
| Source ID | ACH-002654_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg306Ter (c.916C>T) | Heterozygous | Germline | PubMed=16418264 |
| MutationSimple | KRAS | p.Gly12Cys (c.34G>T) | Unspecified | - | PubMed=21173094 |
| MutationSimple | APC | p.Arg1114Ter (c.3340C>T) | Heterozygous | - | from parent cell line LoVo |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
11,12
D16S539
9
D18S51
15
D19S433
13,14
D21S11
30
D2S1338
18,19
D3S1358
16
D5S818
11,12
D7S820
9,11
D8S1179
13
FGA
23
Penta D
11
Penta E
11,12
TH01
6,9.3
TPOX
8,11
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
van Wezel T.
PLoS ONE 12:E0184900-E0184900(2017).