JVE187Homo sapiens (Human)Cancer cell line

Also known as: JVE-187

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_EG23
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age60
Age CategoryAdult
SexFemale

Disease Information

DiseaseColon adenocarcinoma
LineageBowel
SubtypeColon Adenocarcinoma
OncoTree CodeCOAD

DepMap Information

Source TypeDSMZ
Source IDACH-002660_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleKRASp.Lys117Asn (c.351A>C)Homozygous-from parent cell line SKM-1

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12,13
D13S317
9,11
D16S539
11,13
D18S51
19
D19S433
12
D21S11
31,32.2
D2S1338
20,22
D3S1358
15,18
D5S818
11,12
D7S820
9
D8S1179
13
FGA
20,24
Penta D
20
Penta E
12
TH01
6,9
TPOX
11
vWA
14,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.

van Wezel T.

PLoS ONE 12:E0184900-E0184900(2017).

Characterization of novel low passage primary and metastatic colorectal cancer cell lines.

Calame J., Oosting J., Morreau H., van Wezel T.

Oncotarget 7:14499-14509(2016).