JVE528Homo sapiens (Human)Cancer cell line
Also known as: JVE-528
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_EG31 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Colon, ascending[UBERON:UBERON_0001156] |
Donor Information
| Age | 57 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Colon adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Colon Adenocarcinoma |
| OncoTree Code | COAD |
DepMap Information
| Source Type | DSMZ |
|---|---|
| Source ID | ACH-002667_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | KRAS | p.Gly13Asp (c.38G>A) | Heterozygous | Somatic | from parent cell line MDA-MB-231 |
| MutationSimple | APC | p.Arg1450Ter (c.4348C>T) | Unspecified | - | PubMed=24755471 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11,14
D13S317
12
D16S539
9,11
D18S51
17
D19S433
15
D21S11
28,31
D2S1338
17,20
D3S1358
15,16
D5S818
11,12
D7S820
8,10
D8S1179
12
FGA
22
Penta D
3
Penta E
8
TH01
6,9.3
TPOX
8
vWA
15,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
van Wezel T.
PLoS ONE 12:E0184900-E0184900(2017).