YUFULOHomo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_G325
SpeciesHomo sapiens (Human)

Disease Information

DiseaseMelanoma

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleNRASp.Gln61Leu (c.182A>T)Unspecified-PubMed=26214590

Publications

Integrated analysis of tumor samples sheds light on tumor heterogeneity.

Kluger Y.

Yale J. Biol. Med. 85:347-361(2012).

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.

Xu F., Li P.-N., Halaban R., Kluger Y.

BMC Genomics 12:230.1-230.14(2011).

PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.

Krauthammer M., McCusker J.P., Kluger Y., Sznol M.

Pigment Cell Melanoma Res. 23:190-200(2010).