YUHUYHomo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_G327
SpeciesHomo sapiens (Human)
Tissue SourceLymph node[UBERON:UBERON_0000029]

Disease Information

DiseaseCutaneous melanoma

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleBRAFp.Val600Glu (c.1799T>A)Unspecified-PubMed=26214590

Publications

MicroRNA signatures differentiate melanoma subtypes.";

Krauthammer M., Tuck D., Slack F.J., Weidhaas J.B.

Cell Cycle 10:1845-1852(2011).

Phosphoproteomic screen identifies potential therapeutic targets in melanoma.

Muthusamy V., Bosenberg M.W., Krauthammer M., Halaban R., Stern D.F.

Mol. Cancer Res. 9:801-812(2011).

PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.

Krauthammer M., McCusker J.P., Kluger Y., Sznol M.

Pigment Cell Melanoma Res. 23:190-200(2010).