FE-PDHomo sapiens (Human)Cancer cell line
Also known as: FePD, FEPD
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_H614 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Donor Information
| Additional Information |
|
|---|---|
| Age | 46 |
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | ALK-negative anaplastic large cell lymphoma |
|---|---|
| Lineage | Lymphoid |
| Subtype | Anaplastic Large-Cell Lymphoma ALK Negative |
| OncoTree Code | ALCLALKN |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001068_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | STAT3 | p.Gly618Arg (c.1852G>C) | Unspecified | - | PubMed=28356514 |
| MutationSimple | JAK1 | p.Gly1097Val (c.3290_3291delinsTT) | Unspecified | - | PubMed=28356514 |
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.";
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Biol. Chem. 399:511-523(2018).
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Kadin M.E., Del Mistro A., Woessner R.D., Jaffe E.S., Waldmann T.A.
Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017).
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.
Turner S.D., Gambacorti-Passerini C., Chiarle R., Voena C.
Oncogene 35:3854-3865(2016).
Proteomic analysis of anaplastic lymphoma cell lines: identification of potential tumour markers.
Monsarrat B., Delsol G., Payrastre B.
Proteomics 6:3210-3222(2006).
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Drexler H.G., MacLeod R.A.F.
Leukemia 18:1569-1571(2004).
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Quentmeier H., Drexler H.G.
Leukemia 10:142-149(1996).
A CD30-positive T cell line established from an aggressive anaplastic large cell lymphoma, originally diagnosed as Hodgkin's disease.
Menin C., D'Andrea E., Chieco-Bianchi L.
Leukemia 8:1214-1219(1994).
The leukemia-lymphoma cell line factsbook.";
Drexler H.G.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).