Mac-2AHomo sapiens (Human)Cancer cell line
Also known as: PB-2A, McG-2A, MAC2A, MAC-2A
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_H637 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Additional Information |
|
|---|---|
| Age | 47 |
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | ALK-negative anaplastic large cell lymphoma |
|---|---|
| Lineage | Lymphoid |
| Subtype | Anaplastic Large-Cell Lymphoma ALK Negative |
| OncoTree Code | ALCLALKN |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001119_source |
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.";
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Biol. Chem. 399:511-523(2018).
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Kadin M.E., Del Mistro A., Woessner R.D., Jaffe E.S., Waldmann T.A.
Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017).
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Drexler H.G., MacLeod R.A.F.
Leukemia 18:1569-1571(2004).
Constitutive secretion of GM-CSF by three different cell lines derived from a single patient with a progressive cutaneous lymphoproliferative disorder.
Marti R.M., Wasik M.A., Kadin M.E.
Cytokine 8:323-329(1996).
Expression of growth factor/receptor genes in postthymic T cell malignancies.
Su I.-J., Kadin M.E.
Am. J. Pathol. 135:439-445(1989).
Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone.
Davis T.H., Morton C.C., Miller-Cassman R., Balk S.P., Kadin M.E.
N. Engl. J. Med. 326:1115-1122(1992).
The leukemia-lymphoma cell line factsbook.";
Drexler H.G.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).