Z-119Homo sapiens (Human)Cancer cell line

Also known as: Z119

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_IU88
SpeciesHomo sapiens (Human)
Tissue SourceBone marrow[UBERON:UBERON_0002371]

Donor Information

Age25
Age CategoryAdult
SexFemale
Subtype FeaturesBCR-ABL1

Disease Information

DiseaseB-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
LineageLymphoid
SubtypeB-Lymphoblastic Leukemia/Lymphoma with t(9;22)(q34.1;q11.2);BCR-ABL1
OncoTree CodeBLLBCRABL1

DepMap Information

Source TypeATCC
Source IDACH-003101_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
Gene fusionABL1BCR-ABL1, BCR-ABL-BCR exon 1 fused to ABL1 exon 2PubMed=10576511, PubMed=10071072, PubMed=8751477
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";

Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.

Leuk. Res. 23:1055-1060(1999).

Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.

Drexler H.G., MacLeod R.A.F., Uphoff C.C.

Leuk. Res. 23:207-215(1999).

Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.

Janssen J.W.G., Drexler H.G.

Leukemia 11:441-447(1997).

Role of granulocyte-macrophage colony-stimulating factor in Philadelphia (Ph1)-positive acute lymphoblastic leukemia: studies on two newly established Ph1-positive acute lymphoblastic leukemia cell lines (Z-119 and Z-181).

Ouspenskaia M.V., Hirsch-Ginsberg C.F., Huh Y.O., Yee G., Kurzrock R.

J. Cell. Physiol. 166:618-630(1996).

The leukemia-lymphoma cell line factsbook.";

Drexler H.G.

(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).