YUSTEHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_J527 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Not specified |
Disease Information
| Disease | Cutaneous melanoma |
|---|
DepMap Information
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | BRAF | p.Val600Glu (c.1799T>A) | Unspecified | - | PubMed=26214590 |
Publications
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Schlessinger J., Lifton R.P., Halaban R.
Nat. Genet. 47:996-1002(2015).
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.
Nat. Genet. 44:1006-1014(2012).
Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.
Xu F., Li P.-N., Halaban R., Kluger Y.
BMC Genomics 12:230.1-230.14(2011).