YUNIBOHomo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_J535
SpeciesHomo sapiens (Human)

Disease Information

DiseaseCutaneous melanoma

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleBRAFp.Val600Lys (c.1798_1799delGTinsAA)Heterozygous-from parent cell line YUSIT1

Publications

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.

Schlessinger J., Lifton R.P., Halaban R.

Nat. Genet. 47:996-1002(2015).

Integrated analysis of tumor samples sheds light on tumor heterogeneity.

Kluger Y.

Yale J. Biol. Med. 85:347-361(2012).

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.

Xu F., Li P.-N., Halaban R., Kluger Y.

BMC Genomics 12:230.1-230.14(2011).