YUSARIHomo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_K022
SpeciesHomo sapiens (Human)
Tissue SourcePleural effusion[UBERON:UBERON_0000175]

Disease Information

DiseaseCutaneous melanoma

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleBRAFp.Val600Glu (c.1799T>A)Unspecified-PubMed=26214590

Publications

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.

Schlessinger J., Lifton R.P., Halaban R.

Nat. Genet. 47:996-1002(2015).

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.

Nat. Genet. 44:1006-1014(2012).