YD-8Homo sapiens (Human)Cancer cell line
Also known as: YD8
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_L079 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Oral cavity, tongue[UBERON:UBERON_0001723] |
Donor Information
| Age | 46 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Squamous cell carcinoma of the oral tongue |
|---|---|
| Lineage | Head and Neck |
| Subtype | Oral Cavity Squamous Cell Carcinoma |
| OncoTree Code | OCSC |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000630_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg273His (c.818G>A) | Homozygous | - | Unknown, PubMed=16264262 |
| MutationSimple | KRAS | p.Gly138Val (c.413G>T) | Heterozygous | - | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10
D13S317
8,10
D16S539
9,11
D18S51
15,16
D21S11
29,30
D3S1358
15,16
D5S818
12
D7S820
10,13
D8S1179
13,16
FGA
24
Penta D
13
Penta E
12,15
TH01
7,9
TPOX
8,11
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The influence of p53 mutation status on the anti-cancer effect of cisplatin in oral squamous cell carcinoma cell lines.
Jo D.-W., Kim Y.-K., Yun P.-Y.
J. Korean Assoc. Oral Maxillofac. Surg. 42:337-344(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes.
Jung C.-K., Park W.-S., Nam S.-W., Eun J.-W., Kang J.-H.
Int. J. Oncol. 43:383-393(2013).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).