HCC1438Homo sapiens (Human)Cancer cell line
Also known as: Hamon Cancer Center 1438, HCC-1438
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_L088 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Lung[UBERON:UBERON_0002048] |
Donor Information
| Age | 43 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Lung large cell carcinoma |
|---|---|
| Lineage | Lung |
| Subtype | Large Cell Lung Carcinoma |
| OncoTree Code | LCLC |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000891_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Lys139fs (c.415delG) | Unspecified | - | PubMed=10353731 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
12
D13S317
11
D16S539
15
D18S51
14,20
D19S433
14
D21S11
32.2
D2S1338
19
D3S1358
15
D5S818
11,13
D7S820
10
D8S1179
14,15
FGA
19,24
Penta D
7,11
Penta E
11,13
TH01
6,7
TPOX
8
vWA
17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
Aldige C.R., Wistuba I.I., Minna J.D.
J. Cell. Biochem. 121:3986-3999(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
Chemistry-first approach for nomination of personalized treatment in lung cancer.
Posner B.A., Minna J.D., Kim H.S., White M.A.
Cell 173:864-878.e29(2018).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
Comparison of features of human lung cancer cell lines and their corresponding tumors.
Ashfaq R., Minna J.D., Gazdar A.F.
Clin. Cancer Res. 5:991-1000(1999).