P2UR/K-562Homo sapiens (Human)Cancer cell line
Also known as: P2URK562
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_L434 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Pleural effusion[UBERON:UBERON_0000175] |
Donor Information
| Age | 53 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Chronic myeloid leukemia |
|---|---|
| Lineage | Myeloid |
| Subtype | Chronic Myeloid Leukemia, BCR-ABL1+ |
| OncoTree Code | CMLBCRABL1 |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-002061_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Gln136fs*13 (c.406_407insC) | Homozygous | - | from parent cell line K-562 |
| Gene fusion | ABL1 | BCR-ABL1, BCR-ABL | - | BCR exon 1 fused to ABL1 exon 2 | PubMed=10576511, PubMed=10071072, PubMed=8751477 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
9,10
D13S317
8
D16S539
11,12
D5S818
11,12
D7S820
9,11
TH01
9.3
TPOX
8,9
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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