NZOV9Homo sapiens (Human)Cancer cell line

Also known as: New Zealand OVarian line 9, NZOV-9

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_LJ73
SpeciesHomo sapiens (Human)
Tissue SourceOvary[UBERON:UBERON_0000992]

Donor Information

Age47
Age CategoryAdult
SexFemale

Disease Information

DiseaseEndometrioid carcinoma of ovary
LineageOvary/Fallopian Tube
SubtypeEndometrioid Ovarian Cancer
OncoTree CodeEOV

DepMap Information

Source TypeCellBank Australia
Source IDACH-001991_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimplePTENp.Arg130Gly (c.388C>G)Homozygous-Unknown, Unknown, PubMed=28273451
MutationSimplePIK3CAp.Tyr1021Cys (c.3062A>G)Unspecified-Unknown, Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
9,11
D13S317
12,13
D16S539
12,13
D18S51
14,18
D19S433
14
D21S11
28,30
D2S1338
21,22
D3S1358
15,18
D5S818
12,13
D7S820
10,11
D8S1179
13
FGA
22,24
Penta D
11,12
Penta E
10,15
TH01
6,7
TPOX
8,11
vWA
18
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Activin is a potent growth suppressor of epithelial ovarian cancer cells.

Shelling A.N.

Cancer Lett. 285:157-165(2009).

Resistance mechanisms determining the in vitro sensitivity to paclitaxel of tumour cells cultured from patients with ovarian cancer.

van Zijl P.L.

Eur. J. Cancer 31A:230-237(1995).