MaPaC-HS-77Homo sapiens (Human)Cancer cell line

Also known as: CL4, P4-CL, MaPac-77, MAPACHS77, MAPAC-HS-77

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_LM84
SpeciesHomo sapiens (Human)
Tissue SourcePancreas[UBERON:UBERON_0001264]

Donor Information

Age64
Age CategoryAdult
SexMale

Disease Information

DiseasePancreatic ductal adenocarcinoma
LineagePancreas
SubtypePancreatic Adenocarcinoma
OncoTree CodePAAD

DepMap Information

Source TypeDSMZ
Source IDACH-002672_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Ala159Asp (c.476C>A)Homozygous-PubMed=28683746, PubMed=24755471, PubMed=24042735, PubMed=16418264, PubMed=9000147, PubMed=7651727
MutationSimpleKRASp.Gly12Val (c.35G>T)HeterozygousAcquiredUnknown, Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11
D13S317
11,13
D16S539
9,11
D18S51
17
D19S433
12,15
D21S11
28
D2S1338
17,23
D3S1358
14
D5S818
12,13
D7S820
10,11
D8S1179
13,14
FGA
19,23
Penta D
13
Penta E
11,12
TH01
6,9.3
TPOX
8,11
vWA
17,19
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers.

Witt S., Rueckert F., Gaiser T.

Sci. Rep. 10:17895-17895(2020).