MONHomo sapiens (Human)Cancer cell line
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_M846 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Abdomen[UBERON:UBERON_0000916] |
Donor Information
| Age Category | Pediatric |
|---|---|
| Sex | Male |
Disease Information
| Disease | Rhabdoid tumor |
|---|---|
| Lineage | Soft Tissue |
| Subtype | Extrarenal Rhabdoid Cancer |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001128_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene deletion | SMARCB1 | - | Homozygous | - | PubMed=11921280 |
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.";
Sorin M., Yung E., Wu X.-H., Kalpana G.V.
Retrovirology 3:56.1-56.15(2006).
hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors.
Mairal A., Delattre O., Aurias A.
Cancer Res. 59:3152-3156(1999).