1273/99Homo sapiens (Human)Cancer cell line
Also known as: 1273, 127399, 1273-99
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_N588 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age Category | Pediatric |
|---|---|
| Sex | Male |
Disease Information
| Disease | Synovial sarcoma |
|---|---|
| Lineage | Soft Tissue |
| Subtype | Synovial Sarcoma |
| OncoTree Code | SYNS |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001270_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene fusion | SS18 | SS18-SSX2 | - | - | Unknown, PubMed=14744540 |
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
Wardelmann E., Schirmacher P., von Deimling A., Mechtersheimer G.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014).
SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: a gain of function of the t(X;18)(p11.2;q11.2) translocation.
Bartolazzi A., Brodin B., Mandahl N., Larsson O.
Cancer Res. 62:3861-3867(2002).