HFHomo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_UI84
SpeciesHomo sapiens (Human)
Tissue SourcePleural effusion[UBERON:UBERON_0000175]

Donor Information

Age77
Age CategoryAdult
SexMale

Disease Information

DiseaseDiffuse large B-cell lymphoma
LineageLymphoid
SubtypeGerminal Center B-Cell Type
OncoTree CodeGCB

DepMap Information

Source TypeATCC
Source IDACH-003108_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12
D13S317
11,13
D16S539
9,12
D5S818
11
D7S820
10,13
TH01
7
TPOX
8
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Strategic therapeutic targeting to overcome venetoclax resistance in aggressive B-cell lymphomas.

Medeiros L.J., Ford R.J. Jr., Nomie K., Zhang L., Wang M.

Clin. Cancer Res. 24:3967-3980(2018).

Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma.

Pham L.V.

Oncotarget 9:346-360(2018).

Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-kappaB-inducing kinase while activating both canonical and alternative nuclear factor-kappaB pathways.

Vega-Vazquez F., Medeiros L.J., Ford R.J. Jr.

Blood 117:200-210(2011).

An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas.

Pham L.V., Tamayo A.T., Li C.-P., Bueso-Ramos C.E., Ford R.J. Jr.

Blood 116:3899-3906(2010).