F5Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_V616
SpeciesHomo sapiens (Human)

Donor Information

Age CategoryUnknown
SexMale

Disease Information

DiseaseMeningioma
LineageCNS/Brain
SubtypeMeningioma
OncoTree CodeMNG

DepMap Information

Source TypeAcademic lab
Source IDACH-001067_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleNRASp.Gln61Lys (c.181C>A)UnspecifiedAcquired during resistance selection processPubMed=26214590
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Tumor-derived cell culture model for the investigation of meningioma biology.

Anderson M.P., Uhlmann E.N., Kipper F.C., Krichevsky A.M.

J. Neuropathol. Exp. Neurol. 80:1117-1124(2021).

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Golub T.R., Root D.E., Hahn W.C.

Sci. Data 1:140035-140035(2014).

Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.

Yazaki T., Manz H.J., Rabkin S.D., Martuza R.L.

Cancer Res. 55:4752-4756(1995).

Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470.

Rabkin S.D., Martuza R.L.

J. Neurooncol. 23:23-29(1995).