HCC827 GR5Homo sapiens (Human)Cancer cell line
Also known as: HCC827GR5, HCC-827-GR5, HCC827-GR5
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_V622 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Lung[UBERON:UBERON_0002048] |
Donor Information
| Age | 39 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Lung adenocarcinoma |
|---|---|
| Lineage | Lung |
| Subtype | Lung Adenocarcinoma |
| OncoTree Code | LUAD |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-000029_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Val218del (c.646_648GTG[2]) (c.652_654delGTG) | Homozygous | - | PubMed=31541927 |
| MutationSimple | EGFR | p.Glu746_Ala750del (c.2236_2250del15) | Unspecified | - | PubMed=16105816 |
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Golub T.R., Root D.E., Hahn W.C.
Sci. Data 1:140035-140035(2014).
TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation.
Nakagawa K.
Mol. Cancer Ther. 9:2785-2792(2010).