SCCOHT-1Homo sapiens (Human)Cancer cell line
Also known as: Small Cell Carcinoma of the Ovary, Hypercalcemic Type-1, SCCOHT1
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_VU69 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Ovary[UBERON:UBERON_0000992] |
Donor Information
| Age | 31 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Small cell carcinoma of the ovary |
|---|---|
| Lineage | Ovary/Fallopian Tube |
| Subtype | Small Cell Carcinoma of the Ovary |
| OncoTree Code | SCCO |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001279_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | SMARCA4 | p.Arg1077Ter (c.3229C>T) | Heterozygous | - | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,11
D13S317
8,12
D16S539
9,13
D18S51
13
D21S11
28,31.2
D3S1358
15,17
D5S818
11,12
D7S820
10,11
D8S1179
13,14
FGA
16,25
Penta D
12,15
Penta E
10,13
TH01
7,8
TPOX
8,9
vWA
14,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.
Bowtell D.D.L., Weissman B.E., Trent J.M., Gilks C.B., Huntsman D.G.
J. Pathol. 238:389-400(2016).