ICC5Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_VV28
SpeciesHomo sapiens (Human)
Tissue SourceLiver[UBERON:UBERON_0002107]

Donor Information

Age73
Age CategoryAdult
SexMale

Disease Information

DiseaseCholangiocarcinoma
LineageBiliary Tract
SubtypeIntrahepatic Cholangiocarcinoma
OncoTree CodeIHCH

DepMap Information

Source TypeAcademic lab
Source IDACH-001845_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleIDH1p.Arg132Val (c.394_395CG>GT)Unspecified-Unknown, PubMed=27231123

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
11,12
D13S317
9,14
D16S539
13
D18S51
15,17
D21S11
28,32.2
D3S1358
14
D5S818
12,13
D7S820
10
D8S1179
14
FGA
23,25
Penta D
10,11
Penta E
9,11
TH01
9,10
TPOX
8
vWA
21
Gene Expression Profile
Gene expression levels and statistical distribution
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Publications

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.

Vazquez F., Getz G., Bardeesy N.M.

bioRxiv 2024:07.04.601970-07.04.601970(2024).

Development and characterization of human primary cholangiocarcinoma cell lines.

Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.

Am. J. Pathol. 192:1200-1217(2022).

Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.

Bardeesy N.M.

Cancer Discov. 6:727-739(2016).