OANC1Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_W891
SpeciesHomo sapiens (Human)
Tissue SourceEsophagus[UBERON:UBERON_0001043]

Donor Information

Age44
Age CategoryAdult
SexMale

Disease Information

DiseaseAdenocarcinoma of the esophagus
LineageEsophagus/Stomach
SubtypeEsophageal Adenocarcinoma
OncoTree CodeESCA

DepMap Information

Source TypeAcademic lab
Source IDACH-002703_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Glu286Lys (c.856G>A)Homozygous-PubMed=17332242, PubMed=16960149
MutationSimpleSMAD4p.Arg445Ter (c.1333C>T)Homozygous-from parent cell line OV-90

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
9
D13S317
8
D16S539
13
D18S51
19
D21S11
31
D3S1358
15
D5S818
13
D7S820
10,12
D8S1179
15
FGA
22
Penta D
11
Penta E
7,10
TH01
7
TPOX
8,12
vWA
18
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Characterization of a novel tumorigenic esophageal adenocarcinoma cell line: OANC1.

Phillips W.A.

Dig. Dis. Sci. 59:78-88(2014).