HG-3Homo sapiens (Human)Transformed cell line
Also known as: HG3
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_Y547 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Donor Information
| Age | 70 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | B-cell chronic lymphocytic leukemia |
|---|---|
| Lineage | Lymphoid |
| Subtype | B-Lymphoblastic Leukemia/Lymphoma |
| OncoTree Code | BLL |
DepMap Information
| Source Type | DSMZ |
|---|---|
| Source ID | ACH-001520_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11,14
D13S317
11,13
D16S539
9,12
D18S51
14,16
D19S433
15,16
D21S11
29,30
D2S1338
17
D3S1358
17,18
D5S818
11
D7S820
8,13
D8S1179
11,15
FGA
23,24
Penta D
9,10
Penta E
11,12
TH01
7,9.3
TPOX
8,12
vWA
17,20
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
The LL-100 panel: 100 cell lines for blood cancer studies.";
MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G.
Sci. Rep. 9:8218-8218(2019).
CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia.
Lauria F., Russo G.L.
Oncotarget 8:42571-42587(2017).
Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation.
Zaborski M., Drexler H.G.
Oncotarget 7:63456-63465(2016).
Molecular characterization of neoplastic and normal 'sister' lymphoblastoid B-cell lines from chronic lymphocytic leukemia.
Jurlander J., Klein E., Weit N., Herling M., Rosenquist R., Rosen A.
Leuk. Lymphoma 54:1769-1779(2013).