YBT-5Homo sapiens (Human)Cancer cell line

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_YJ20
SpeciesHomo sapiens (Human)
Tissue SourceBone marrow[UBERON:UBERON_0002371]

Disease Information

DiseaseAcute myeloid leukemia

DepMap Information

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
Gene fusionKMT2AKMT2A-MLLT3, MLL-MLLT3, MLL-AF9--PubMed=31701557

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
10,12
D12S391
18,20
D13S317
8,12
D16S539
12,13
D18S51
13,20
D19S433
15,15.2
D21S11
30,31.2
D2S1338
23
D3S1358
17
D5S818
11
D6S1043
14,17
D7S820
12
D8S1179
13
FGA
21,24
vWA
14,19

Publications

Establishment and characterization of a DOT1L inhibitor-sensitive human acute monocytic leukemia cell line YBT-5 with a novel KMT2A-MLLT3 fusion.

Tang B., Miao S.-C., Ma N., Cen X.-N., Ren H.-Y., Dong Y.-J.

Hematol. Oncol. 37:617-625(2019).