NCC-MPNST1-C1Homo sapiens (Human)Cancer cell line
Also known as: NCCMPNST1C1
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_YU12 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 37 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Neurofibromatosis type 1 |
|---|---|
| Lineage | Peripheral Nervous System |
| Subtype | Malignant Peripheral Nerve Sheath Tumor |
| OncoTree Code | MPNST |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-002799_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | BRCA2 | p.Lys1872Ter (c.5614A>T) | Heterozygous | - | PubMed=32099531 |
| Gene deletion | TSC1 | - | Homozygous | - | PubMed=32099531 |
| Gene deletion | TP53 | - | Homozygous | 2 out of 3 copies | from parent cell line HL-60 |
| Gene deletion | CDKN2A | - | Homozygous | Possible | PubMed=26870271 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
11,12
D16S539
10,11
D21S11
30,31
D5S818
7,13
D7S820
10.3,11
TH01
6
TPOX
11
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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