NCC-MPNST3-C1Homo sapiens (Human)Cancer cell line
Also known as: NCCMPNST3C1
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_YU14 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 72 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Neurofibromatosis type 1 |
|---|---|
| Lineage | Peripheral Nervous System |
| Subtype | Malignant Peripheral Nerve Sheath Tumor |
| OncoTree Code | MPNST |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-002801_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | PIK3CA | p.Glu542Lys (c.1624G>A) | Unspecified | - | PubMed=31541927 |
| MutationSimple | NF1 | p.Arg816Ter (c.2446C>T) | Heterozygous | Germline | PubMed=32099531 |
| Gene deletion | MTOR | - | Homozygous | - | PubMed=32099531 |
| Gene deletion | CDKN2A | - | Homozygous | Possible | PubMed=26870271 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
12
D13S317
8
D16S539
11
D21S11
30
D5S818
12,13
D7S820
12,13
TH01
9
TPOX
8,11
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines
Loading gene expression data...